Thesis
Molecular imaging of DNA damage repair
- Abstract:
-
Nuclear imaging has the ability to non-invasively probe target expression, drug pharmacokinetics, and monitor treatment response. With many cancer therapies inducing DNA damage to overwhelm tumour cells into arrest, there has been a push to investigate the DNA damage response with regards to understanding the key proteins involved and the development of DDR inhibitors to enhance current DNA damaging therapies. The use of DDR inhibitor radiotracers with PET or SPECT could allow scientists to q...
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Authors
Contributors
+ Cornelissen, B
Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Sub department:
CRUK/MRC Ox Inst for Radiation Oncology
Role:
Supervisor
+ Ryan, A
Role:
Supervisor
+ Blackford, A
Institution:
University of Oxford
Division:
MSD
Role:
Supervisor
ORCID:
0000-0003-1979-021X
+ Smith, G
Role:
Supervisor
Funding
+ Medical Research Council
More from this funder
Funder identifier:
http://dx.doi.org/10.13039/501100000265
Funding agency for:
Cornelissen, B
Grant:
MR/R01695X/1
Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
-
English
- Keywords:
- Subjects:
- Deposit date:
-
2023-01-03
Related Items
Terms of use
- Copyright holder:
- Fraser, CR
- Copyright date:
- 2022
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