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Hepatic resection following selective internal radiotherapy in the FOXFIRE clinical trial: survival, safety, and histopathology

Abstract:

Colorectal cancer (CRC) commonly metastasises to the liver and is a leading cause of cancer-related death. The FOXFIRE trial compared the safety and efficacy of radiosensitising chemotherapy (OxMdG: oxaliplatin, 5-fluorouracil and folic acid) with selective internal radiotherapy (SIRT) using yttrium-90 resin microspheres (SIR-Spheres®; Sirtex Medical Limited) to OxMdG alone as first-line management for liver-dominant metastatic CRC. In patients downsized to potentially-curative hepatic resect...

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Publication status:
In press
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Centre for Statistics in Medicine
Role:
Author
ORCID:
0000-0002-3006-8730
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Oncology
Role:
Author
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Publisher:
National Cancer Research Institute Publisher's website
Journal:
National Cancer Research Institute Cancer Conference 2018 Journal website
Host title:
National Cancer Research Institute Cancer Conference 2018
Publication date:
2018-01-01
Acceptance date:
2018-06-25
Source identifiers:
859283
Pubs id:
pubs:859283
UUID:
uuid:f1f09a89-8aa2-4068-a698-eb9d0bab9299
Local pid:
pubs:859283
Deposit date:
2018-06-25

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