- Abstract:
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Background The size of any causal contribution of central and general adiposity to CKD risk and the underlying mechanism of mediation are unknown.
Methods Data from 281,228 UK Biobank participants were used to estimate the relevance of waist-to-hip ratio and body mass index (BMI) to CKD prevalence. Conventional approaches used logistic regression. Genetic analyses used Mendelian randomization (MR) and data from 394 waist-to-hip ratio and 773 BMI-as...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Files:
-
- Publisher copy:
- 10.1681/asn.2020050679
-
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- Publisher:
- American Society of Nephrology Publisher's website
- Journal:
- Journal of the American Society of Nephrology Journal website
- Place of publication:
- United States
- Publication date:
- 2020-10-30
- Acceptance date:
- 2020-09-10
- DOI:
- EISSN:
-
1533-3450
- ISSN:
-
1046-6673
- Pmid:
-
33127858
- Pubs id:
-
1140348
- Local pid:
- pubs:1140348
- Language:
- English
- Keywords:
- Format:
- Print-Electronic
- Copyright holder:
- American Society of Nephrology
- Copyright date:
- 2020
- Rights statement:
- © 2021 by the American Society of Nephrology. This article is freely available upon publication through the Author Choice program.
Journal article
Conventional and genetic evidence on the association between adiposity and CKD
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