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Clinical relevance of positive voltage-gated potassium channel (VGKC)-complex antibodies: Experience from a tertiary referral centre

Abstract:

Background: Voltage-gated potassium channel (VGKC)-complex antibodies can be associated with a range of immunotherapy-responsive clinical presentations including limbic encephalitis, Morvan 's syndrome and acquired neuromyotonia. However, there are patients with positive levels in whom the significance is uncertain. Objective To evaluate the clinical significance associated with positive (>100 pM) VGKC-complex antibodies. Methods: Over a 4-year period, 1053 samples were sent for testing of...

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Publisher copy:
10.1136/jnnp-2013-305218

Authors


Paterson, RW More by this author
Armstrong, R More by this author
Vincent, A More by this author
Schott, JM More by this author
Publisher:
BMJ Publishing Group
Journal:
Journal of Neurology, Neurosurgery and Psychiatry
Volume:
85
Issue:
6
Pages:
625-630
Publication date:
2014-06-01
DOI:
EISSN:
1468-330X
ISSN:
0022-3050
URN:
uuid:f108731f-c33e-4024-9cf1-bc1ebe66d31c
Source identifiers:
466334
Local pid:
pubs:466334
Language:
English

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