Nucleus accumbens core dopamine during Go-NoGo task

Dataset can be accessed at:
https://data.mrc.ox.ac.uk/data-set/nucleus-accumbens-core-dopamine-during-go-nogo-task

This dataset is licensed under CC BY-SA 4.0.

Fast-scan cyclic voltammetry (FCV) data recorded in the nucleus accumbens core (NAcc) of rats carrying out a Go-NoGo task.

First Published In
Syed EC, Grima LL, Magill PJ, Bogacz R, Brown P, Walton ME
Action initiation shapes mesolimbic dopamine encoding of future rewards.
2016.Nat. Neurosci., 19(1):34-6.


Channels recorded are either chan 0 - recorded in the right hemisphere or chan 1 - recorded in the left hemisphere. For study 1 there is only one channel recorded per animal in NAcc. For study 2 there is either one or two channels recorded in each animal. If there were two channels recorded these were recorded on separate dates. 

The FCV data file is named 'Stacked_Qcutoff'. Data provided here has undergone chemometric analysis and values are the recorded current (nA) corresponding to dopamine oxidation.  At each timepoint when the chemometric analysis failed to resolve dopamine from the recorded signal, the value is given as 'NaN'.

The data is a tab separated file, with continuous recordings organised in columns. The first column holds timestamps (resolution is 10 Hz) and all subsequent columns represent one trial. 

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Behavioural Data was recorded with MED-PC and is saved in text files found in the folder corresponding to the animal. 

For study 1 these will be named 'gonogo_rat(RatNumber)_(DateOfRecording)'. There is one behavioural file per animal.

For study 2 these will be named '009_(RatNumber)_step6v_(DateOfRecording). There are two behavioural files per animal.


Variable A contains overall data:
A(4) = number of GO Right Trials
A(5) = number of GO Left Trials
A(6) = number of NOGO Trials

A(7) = number of Rewarded GO Right Trials
A(8) = number of Rewarded GO Left Trials
A(9) = number of Rewarded NOGO Trials


Variable E contains event numbers:
100 = Start Session & End Session
101 = Start Next Trial
102 = Start Trial Over
103 = Start Task
201 = Go Cue Right
202 = Go Cue Left
203 = No-Go Cue
301 = Nose-poke counter IN TASK
3011 = Right Lever press FIRST TIME
3012 = Successful GO RIGHT
3015 = Incorrect Right Press
3021 = Go lever press left FIRST TIME
3022 = Successful GO LEFT
3025 = Incorrect Left Press
303 = No-Go nosepoke exit (correct or error)
3032 = Successful NO-GO
400 = Reward delivery
401 = Reward collected
5011 = Incorrect GO RIGHT Trial
5012 = Incorrect GO LEFT Trial
5013 = Incorrect NO-GO Trial
5021 = Max Response Time Exceeded GO RIGHT
5022 = Max Response Time Exceeded GO LEFT
503 = End of Error Time
601 = Nose-poke counter OUT OF TASK
602 = Food Tray entry OUT OF TASK (no reward)
603 = Left Lever Press OUT OF TASK
604 = Right Lever Press OUT OF TASK


Variable T contains the timestamps for each event in variable E. MED-PC has a 10ms resolution