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One R or the other – an experimental bioethics approach to 3R dilemmas in animal research

Abstract:
Sacrificial dilemmas such as the trolley problem play an important role in experimental philosophy (x-phi). But it is increasingly argued that, since we are not likely to encounter runaway trolleys in our daily life, the usefulness of such thought experiments for understanding moral judgments in more ecologically valid contexts may be limited. However, similar sacrificial dilemmas are experienced in real life by animal research decision makers. As part of their job, they must make decisions about the suffering, and often the death, of many non-human animals. For this reason, a context-specific investigation of so-called “3R dilemmas” (i.e., dilemmas where there is a conflict between the principles of replacement, reduction, and refinement of the use of animals in research) is essential to improve the situation of both non-human animals and human stakeholders. An approach well suited for such investigation is experimental philosophical bioethics (“bioxphi”), which draws on methods similar to x-phi to probe more realistic, practical scenarios with an eye to informing normative debates and ethical policy. In this article, we argue for a need to investigate 3R dilemmas among professional decision-makers using the tools of bioxphi. In a first step, we define 3R dilemmas and discuss previous investigations of professionals’ attitudes in such cases. In a second step, we show how bioxphi is a promising method to investigate the whys and hows of professional decision-making in 3R dilemmas. In a last step, we provide a bioxphi template for 3R dilemmas, give recommendations on its use, explore the normative relevance of data collected by such means, and discuss important limitations.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1007/s11019-024-10221-y

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Role:
Author
ORCID:
0000-0001-8944-1504
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Role:
Author
ORCID:
0000-0001-8180-6927
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Institution:
University of Oxford
Division:
HUMS
Department:
Philosophy
Role:
Author
ORCID:
0000-0001-9691-2888
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Role:
Author
ORCID:
0000-0002-4249-7399
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Role:
Author
ORCID:
0000-0001-8783-1437


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Funder identifier:
https://ror.org/00yjd3n13


Publisher:
Springer
Journal:
Medicine, Health Care and Philosophy More from this journal
Volume:
27
Issue:
4
Pages:
497-512
Publication date:
2024-08-17
Acceptance date:
2024-07-27
DOI:
EISSN:
1572-8633
ISSN:
1386-7423
Pmid:
39153014


Language:
English
Keywords:
Pubs id:
2023176
Local pid:
pubs:2023176
Deposit date:
2024-08-29

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