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The effect of dose escalation on gastric toxicity when treating lower oesophageal tumours: A radiobiological investigation

Abstract:

Purpose: Using radiobiological modelling to estimate normal tissue toxicity, this study investigates the effects of dose escalation for concurrent chemoradiation therapy (CRT) in lower third oesophageal tumours on the stomach. Methods and materials: 10 patients with lower third oesophageal cancer were selected from the SCOPE 1 database (ISCRT47718479) with a mean planning target volume (PTV) of 348 cm3. The original 3D conformal plans (50Gy3D) were compared to newly created RapidArc plans of ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/s13014-015-0537-y

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Role:
Author
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Publisher:
BioMed Central Publisher's website
Journal:
Radiation Oncology Journal website
Volume:
10
Issue:
1
Article number:
10:236
Publication date:
2015-11-19
DOI:
EISSN:
1748-717X
Source identifiers:
578886
Pubs id:
pubs:578886
UUID:
uuid:ef79bf23-86dd-4084-9938-4b4a659fed18
Local pid:
pubs:578886
Deposit date:
2015-12-09

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