Endogenous viral elements in animal genomes.

Journal article

Integration into the nuclear genome of germ line cells can lead to vertical inheritance of retroviral genes as host alleles. For other viruses, germ line integration has only rarely been documented. Nonetheless, we identified endogenous viral elements (EVEs) derived from ten non-retroviral families by systematic in silico screening of animal genomes, including the first endogenous representatives of double-stranded RNA, reverse-transcribing DNA, and segmented RNA viruses, and the first endoge...

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Authors: Katzourakis, A; Gifford, R

• Publication status: Published
• Journal: PLoS genetics
• Volume: 6
• Issue: 11
• Pages: e1001191
• Publication date: 2010-11-01
• DOI: 10.1371/journal.pgen.1001191
• EISSN: 1553-7404
• ISSN: 1553-7390
• Language: English
• Keywords: DNA Viruses; Virus Replication; Base Sequence; RNA Viruses; Genes, Viral; Animals; Mutagenesis, Insertional; Genetic Variation; Gene Flow; Computational Biology; Primates; Fossils; Phylogeny; Open Reading Frames; Genome