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Role of interleukin 36γ in host defense against tuberculosis

Abstract:

Tuberculosis remains a major killer worldwide, not the least because of our incomplete knowledge of protective and pathogenic immune mechanism. The roles of the interleukin 1 (IL-1) and interleukin 18 pathways in host defense are well established, as are their regulation through the inflammasome complex. In contrast, the regulation of interleukin 36γ (IL-36γ), a recently described member of the IL-1 family, and its immunological relevance in host defense remain largely unknown. Here we show t...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/infdis/jiw152

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Role:
Author
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Max Planck Society More from this funder
Publisher:
Oxford University Press Publisher's website
Journal:
Journal of Infectious Diseases Journal website
Volume:
214
Issue:
3
Pages:
464–474
Publication date:
2016-04-18
Acceptance date:
2016-04-07
DOI:
EISSN:
1537-6613
ISSN:
0022-1899
Pubs id:
pubs:939833
URN:
uri:ef04608b-e264-4ba5-a73f-779c747ab2aa
UUID:
uuid:ef04608b-e264-4ba5-a73f-779c747ab2aa
Local pid:
pubs:939833

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