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Journal article

Proposed primary endpoints for use in clinical trials that compare treatment options for bloodstream infection in adults: a consensus definition.

Abstract:

Objectives

To define standardised endpoints to aid the design of trials that compare antibiotic therapies for bloodstream infection (BSI).

Methods

Prospective studies, randomised trials or registered protocols comparing antibiotic therapies for BSI, published from 2005 to 2016, were reviewed. Consensus endpoints for BSI studies were defined using a modified Delphi process.

Results

Different primary and secondary endpoints were defined for pilot (...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Files:
Publisher copy:
10.1016/j.cmi.2016.10.023

Authors


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Grant:
Australian Postgraduate Award
German Centre for Infection Research More from this funder
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Publisher:
Elsevier Publisher's website
Journal:
Clinical Microbiology and Infection Journal website
Volume:
23
Issue:
8
Pages:
533-541
Publication date:
2016-11-05
Acceptance date:
2016-10-21
DOI:
ISSN:
1469-0691
Pubs id:
pubs:660181
URN:
uri:eeeed218-4994-4efa-83af-ca18f518be73
UUID:
uuid:eeeed218-4994-4efa-83af-ca18f518be73
Local pid:
pubs:660181

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