- Abstract:
-
Injections with a hypodermic needle and syringe (HNS) are the current standard of care globally, but the use of needles is not without limitation. While a plethora of needle-free injection devices exist, vaccine reformulation is costly and presents a barrier to their widespread clinical application. To provide a simple, needle-free, and broad-spectrum protein antigen delivery platform, we developed novel potassium-doped hydroxyapatite (K-Hap) microparticles with improved protein loading capab...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Accepted Manuscript
- Files:
-
-
(vnd.openxmlformats-officedocument, 890.7kb)
-
- Publisher copy:
- 10.1128/cvi.00121-15
-
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- Publisher:
- American Society for Microbiology Publisher's website
- Journal:
- Clinical and vaccine immunology : CVI Journal website
- Volume:
- 22
- Issue:
- 5
- Pages:
- 586-592
- Publication date:
- 2015
- DOI:
- EISSN:
-
1556-679X
- ISSN:
-
1556-6811
- URN:
-
uuid:ee7aa39e-7457-4217-ae1d-7d1ee7a6971e
- Source identifiers:
-
517025
- Local pid:
- pubs:517025
- Language:
- English
- Copyright holder:
- American Society for Microbiology
- Copyright date:
- 2015
- Notes:
- Copyright © 2015, American Society for Microbiology.
Journal article
Needle-free dermal delivery of a diphtheria toxin CRM197 mutant on potassium-doped hydroxyapatite microparticles
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Oxford Martin School
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University of Oxford
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