Journal article
Haptoglobin, alpha-thalassaemia and glucose-6-phosphate dehydrogenase polymorphisms and risk of abnormal transcranial Doppler among patients with sickle cell anaemia in Tanzania
- Abstract:
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Transcranial Doppler ultrasonography measures cerebral blood flow velocity (CBFv) of basal intracranial vessels and is used clinically to detect stroke risk in children with sickle cell anaemia (SCA). Co-inheritance in SCA of alpha-thalassaemia and glucose-6-phosphate dehydrogenase (G6PD) polymorphisms is reported to associate with high CBFv and/or risk of stroke. The effect of a common functional polymorphism of haptoglobin (HP) is unknown. We investigated the effect of co-inheritance of the...
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Bibliographic Details
- Publisher:
- Blackwell Publishing Ltd
- Journal:
- British Journal of Haematology More from this journal
- Volume:
- 165
- Issue:
- 5
- Pages:
- 699-706
- Publication date:
- 2014-01-01
- DOI:
- EISSN:
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1365-2141
- ISSN:
-
0007-1048
Item Description
- Language:
-
English
- Keywords:
- Pubs id:
-
pubs:466871
- UUID:
-
uuid:eccfa83c-cc1c-4975-9304-d90b92e8e49e
- Local pid:
-
pubs:466871
- Source identifiers:
-
466871
- Deposit date:
-
2014-06-16
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- Copyright date:
- 2014
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