Ruggero Ceppellini: a perspective on his contributions to genetics and immunology

Journal article

Abstract:: Ruggero Ceppellini, who died at the age of 71 in 1988, was one of the most stimulating and original human geneticists of his generation (1). Ceppellini's outstanding contributions to the genetics of the human blood groups, immunoglobulin allotypes and the HLA system epitomize the study of immunogenetics. By using his considerable skills and insights to unravel the interpretation of the serological data, he made significant contributions to immunology. He is remembered especially for his incisive contributions to the development of the genetics of the HLA system and its nomenclature, including, in particular, his introduction of the term "haplotype," now widely used by geneticists throughout the world, most of whom are unlikely to be aware of its origins.

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Language:: English
Keywords:: transplantation

Ceppellini

HLA antigens

humans

history, 20th Century

haplotype

MLC

human genetics

allergy and immunology

FFR
Pubs id:: 1026962
Local pid:: pubs:1026962
Deposit date:: 2021-01-22

Copyright holder:: Bodmer.
Rights statement:: ©2019 Bodmer. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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