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Thesis

The role of adenosine in remote ischaemic conditioning

Abstract:

Strategies to reduce infarct size in ischaemia-reperfusion (IR) syndromes such as acute myocardial infarction are of high clinical and scientific interest. Remote ischaemic preconditioning (rIPC) is one such strategy but its mechanisms remain incompletely understood. Multiple lines of evidence from animal studies suggest that the endogenous purine nucleoside adenosine is a key mediator of preconditioning pathways but no evidence exists as to adenosine’s role in the more complex physiolog...

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Institution:
University of Oxford
Research group:
Kharbanda
Oxford college:
St Catherine's College
Department:
Medical Sciences Division - Cardiovascular Medicine

Contributors

Role:
Supervisor
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Funding agency for:
Hussain Contractor
Publication date:
2012
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:ebb047e8-fa80-43f2-a498-0d5bfca5b138
Local pid:
ora:7451

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