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Improving the accuracy of biologically effective dose (BED) estimates, from a previously published study, after radiosurgery for acoustic neuromas

Abstract:

Objective
To recalculate biological effective dose values (BED) for radio-surgical treatments of acoustic neuroma from a previous study. BEDs values were previously overestimated by only using beam-on times in calculations, so excluding the important beam-off-times (when deoxyribonucleic acid repair continues) which contribute to the overall treatment time. Simple BED estimations using a mono-exponential approximation may not always be appropriate but if used should in...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.wneu.2022.12.119

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Institution:
University of Oxford
Role:
Author
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Role:
Author
ORCID:
0000-0002-5583-2205
More by this author
Institution:
University of Oxford
Role:
Author
Publisher:
Elsevier
Journal:
World Neurosurgery More from this journal
Volume:
172
Pages:
e130-e143
Publication date:
2022-12-29
Acceptance date:
2022-12-28
DOI:
ISSN:
1878-8750
Language:
English
Keywords:
Pubs id:
1317503
Local pid:
pubs:1317503
Deposit date:
2022-12-31

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