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The inspired sine-wave technique: A novel method to measure lung volume and ventilatory heterogeneity

Abstract:

The inspired sine-wave technique (IST) is a new method that can provide simple, non-invasive cardiopulmonary measurements. Over successive tidal breaths, the concentration of a tracer gas (i.e. nitrous oxide,N2O) is sinusoidally modulated in inspired air. Using a single-compartment tidalventilation lung model, the resulting amplitude/phase of the expired sine wave allows estimation of end-expired lung volume (ELV), pulmonary blood flow and three indices for ventilatory heterogeneity (VH; ELV1...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1113/ep086867

Authors


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ORCID:
0000-0002-8941-3519
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Pacpaco, E More by this author
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; NDM Experimental Medicine
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Publisher:
Wiley Publisher's website
Journal:
Experimental Physiology Journal website
Publication date:
2018-02-19
Acceptance date:
2018-02-15
DOI:
EISSN:
1469-445X
ISSN:
0958-0670
Pubs id:
pubs:826228
URN:
uri:ea94a17b-4f3d-4507-ac01-dd768ccc0415
UUID:
uuid:ea94a17b-4f3d-4507-ac01-dd768ccc0415
Local pid:
pubs:826228

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