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Using curvature power to map the domain of inverse micellar cubic phases: The case of aliphatic aldehydes in 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

Abstract:

Oxylipins, or fatty aldehydes, are a class of molecules produced from membrane lipids as a result of oxidative stress or enzyme-mediated peroxidation. Here we report the effects of two biologically important fatty aldehydes, trans,trans-2,4-decanedienal (DD) and cis-11-hexadecenal (HD), on the phase behavior of the lipid 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) in water. We compare the phase behavior of DD/DOPE and HD/DOPE mixtures to the phase behavior of oleic acid/DOPE mixtures...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1021/acs.langmuir.7b02998

Authors


Burrell, J More by this author
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ORCID:
0000-0002-9903-4993
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Subgroup:
Structural Genomics Consortium
ORCID:
0000-0002-8597-8723
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ORCID:
0000-0003-0702-5772
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ORCID:
0000-0002-8323-7235
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Swedish Research Council More from this funder
School of Pharmacy and Biomolecular Sciences More from this funder
Publisher:
American Chemical Society Publisher's website
Journal:
Langmuir Journal website
Volume:
33
Issue:
44
Pages:
12804-12813
Publication date:
2017-10-05
Acceptance date:
2017-10-04
DOI:
EISSN:
1520-5827
ISSN:
0743-7463
Pubs id:
pubs:737298
URN:
uri:ea73acc3-d3f9-4b12-8aa5-c75a9aec452a
UUID:
uuid:ea73acc3-d3f9-4b12-8aa5-c75a9aec452a
Local pid:
pubs:737298

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