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Imaging ionic flux through individual pores in droplet interface bilayers

Abstract:

Optical measurements of ion flux are a powerful technique when studying the functional properties of ion channels and the dynamics of pore formation in biological membranes. The simultaneous read-out of optical single channel recordings (oSCR) provides an alternative way of measuring electrical activity and is more feasible than parallelising electrical measurements. Channel activity is monitored with ion specific indicator dyes whose response is proportional to the magnitude of the curren...

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Marc Szabo More by this author

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Role:
Supervisor
Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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