Journal article icon

Journal article

Streptococcus suis contains multiple phase-variable methyltransferases that show a discrete lineage distribution

Abstract:

Streptococcus suis is a major pathogen of swine, responsible for a number of chronic and acute infections, and is also emerging as a major zoonotic pathogen, particularly in South-East Asia. Our study of a diverse population of S. suis shows that this organism contains both Type I and Type III phase-variable methyltransferases. In all previous examples, phase-variation of methyltransferases results in genome wide methylation differences, and results in differential regulation of multiple gene...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Publisher copy:
10.1093/nar/gky913

Authors


More by this author
Role:
Author
ORCID:
0000-0002-7994-6995
More from this funder
Name:
Wellcome Trust
Grant:
109385/Z/15/Z
More from this funder
Name:
Royal Society
Grant:
RG8671
Publisher:
Oxford University Press
Journal:
Nucleic Acids Research More from this journal
Volume:
46
Issue:
21
Pages:
11466-11476
Publication date:
2018-10-10
Acceptance date:
2018-10-06
DOI:
EISSN:
1362-4962
ISSN:
0305-1048
Pmid:
30304532
Language:
English
Keywords:
Pubs id:
pubs:971998
UUID:
uuid:e97d45f6-82fb-460e-ab4d-981a7e2623ec
Local pid:
pubs:971998
Source identifiers:
971998
Deposit date:
2019-04-03

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP