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Neuroanatomical correlates of prion disease progression - a 3T longitudinal voxel-based morphometry study

Abstract:

PURPOSE: MRI has become an essential tool for prion disease diagnosis. However there exist only a few serial MRI studies of prion patients, and these mostly used whole brain summary measures or region of interest based approaches. We present here the first longitudinal voxel-based morphometry (VBM) study in prion disease. The aim of this study was to systematically characterise progressive atrophy in patients with prion disease and identify whether atrophy in specific brain structures correla...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1016/j.nicl.2016.10.021

Authors


De Vita, E More by this author
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Department:
Oxford, MSD, Clinical Neurosciences
Porter, MC More by this author
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Grant:
National Prion Monitoring Cohort (grant number 535951)
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Grant:
MR/J014257/2 for GR, and core funding for the MRC Prion Unit, MC-A750-5QU00
Publisher:
Elsevier Publisher's website
Journal:
NeuroImage: Clinical Journal website
Volume:
13
Pages:
89-96
Publication date:
2017
DOI:
ISSN:
2213-1582
Pubs id:
pubs:666678
URN:
uri:e963ba44-85d6-4925-b3b1-396a5dc3ff3b
UUID:
uuid:e963ba44-85d6-4925-b3b1-396a5dc3ff3b
Local pid:
pubs:666678

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