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Neuroanatomical correlates of prion disease progression - a 3T longitudinal voxel-based morphometry study

Abstract:

PURPOSE: MRI has become an essential tool for prion disease diagnosis. However there exist only a few serial MRI studies of prion patients, and these mostly used whole brain summary measures or region of interest based approaches. We present here the first longitudinal voxel-based morphometry (VBM) study in prion disease. The aim of this study was to systematically characterise progressive atrophy in patients with prion disease and identify whether atrophy in specific brain structures correla...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.nicl.2016.10.021

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
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Funding agency for:
Ridgway, G
Grant:
MR/J014257/2
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Grant:
National Prion Monitoring Cohort (grant number 535951
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Grant:
corefundingfortheMRCPrionUnit,MC-A750-5QU00
MR/J014257/2forGR,
Publisher:
Elsevier Publisher's website
Journal:
NeuroImage: Clinical Journal website
Volume:
13
Pages:
89-96
Publication date:
2017-01-01
Acceptance date:
2016-10-28
DOI:
ISSN:
2213-1582
Source identifiers:
666678
Language:
English
Keywords:
Pubs id:
pubs:666678
UUID:
uuid:e963ba44-85d6-4925-b3b1-396a5dc3ff3b
Local pid:
pubs:666678
Deposit date:
2017-01-16

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