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Genome-wide analysis of self-reported risk-taking behaviour and cross-disorder genetic correlations in the UK Biobank cohort

Abstract:

Risk-taking behaviour is a key component of several psychiatric disorders and could influence lifestyle choices such as smoking, alcohol use, and diet. As a phenotype, risk-taking behaviour therefore fits within a Research Domain Criteria (RDoC) approach, whereby identifying genetic determinants of this trait has the potential to improve our understanding across different psychiatric disorders. Here we report a genome-wide association study in 116,255 UK Biobank participants who responded yes...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1038/s41398-017-0079-1

Authors


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Role:
Author
ORCID:
0000-0001-8506-3585
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Psychiatry
Role:
Author
ORCID:
0000-0002-2966-2281
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Role:
Author
ORCID:
0000-0002-5429-3799
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Funding agency for:
Tunbridge, EM
Publisher:
Springer Nature Publisher's website
Journal:
Translational Psychiatry Journal website
Volume:
8
Issue:
1
Pages:
Article: 39
Publication date:
2018-02-02
Acceptance date:
2017-11-13
DOI:
ISSN:
2158-3188
Pubs id:
pubs:823369
URN:
uri:e957fac3-3833-4795-a63c-c07cfdfda774
UUID:
uuid:e957fac3-3833-4795-a63c-c07cfdfda774
Local pid:
pubs:823369
Language:
English

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