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Chloroquine-primaquine versus chloroquine alone to treat Vivax malaria in Afghanistan: An open randomized superiority trial.

Abstract:

Background

Afghanistan’s national guidelines recommend primaquine for radical treatment of P. vivax malaria but this is rarely implemented because of concerns over potential hemolysis in patients who have G6PD deficiency.

Methods

Between August 2009 and February 2014, we conducted an open-label, randomized controlled trial of chloroquine (CQ) alone versus chloroquine plus primaquine (0.25mg base/kg/day for 14 days)(CQ+PQ) in patients aged > 6 months with micr...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.4269/ajtmh.17-0290

Authors


More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; Tropical Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; Tropical Medicine
Role:
Author
Publisher:
American Journal of Tropical Medicine and Hygiene
Journal:
American Journal of Tropical Medicine and Hygiene More from this journal
Publication date:
2017-12-01
Acceptance date:
2017-08-04
DOI:
EISSN:
1476-1645
ISSN:
0002-9637
Pmid:
29141719
Language:
English
Keywords:
Pubs id:
pubs:746809
UUID:
uuid:e904c2ce-e17f-4abe-b3f0-7ccc1698ea25
Local pid:
pubs:746809
Source identifiers:
746809
Deposit date:
2017-12-01

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