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Large-scale analysis of association between polymorphisms in the transforming growth factor beta 1 gene (TGFB1) and osteoporosis: the GENOMOS study.

Abstract:

INTRODUCTION: The TGFB1 gene which encodes transforming growth factor beta 1, is a strong candidate for susceptibility to osteoporosis and several studies have reported associations between bone mineral density (BMD), osteoporotic fractures and polymorphisms of TGFB1, although these studies have yielded conflicting results. METHODS: We investigated associations between TGFB1 polymorphisms and BMD and fracture in the GENOMOS study: a prospective multicenter study involving 10 European researc...

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Publication status:
Published

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Publisher copy:
10.1016/j.bone.2007.11.007

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Journal:
Bone More from this journal
Volume:
42
Issue:
5
Pages:
969-981
Publication date:
2008-05-01
DOI:
EISSN:
1873-2763
ISSN:
8756-3282

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