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Journal article

Pre-clinical development and assessment of viral vectors expressing a fusion antigen of P. falciparum LSA1 and LSAP2 for efficacy against liver-stage malaria

Abstract:

Despite promising progress in malaria vaccine development in recent years, an efficacious subunit vaccine against P. falciparum (Pf) remains to be licensed and deployed. Cell mediated protection from liver-stage malaria is reliant on a sufficient number of antigen specific T cells reaching the liver during the time that parasites are present. A single vaccine expressing two antigens could potentially increase both the size and breadth of antigen specific response, while halving vaccine produc...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1128/IAI.00573-19

Authors


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Name:
Wellcome Trust
Grant:
104750/Z/14/Z
Publisher:
American Society for Microbiology
Journal:
Infection and Immunity More from this journal
Volume:
88
Issue:
2
Pages:
e00573-19
Publication date:
2019-11-18
Acceptance date:
2019-11-14
DOI:
EISSN:
1098-5522
ISSN:
0019-9567
Keywords:
Pubs id:
pubs:1071853
UUID:
uuid:e8a4bbe4-0693-4c00-b6a9-ac56cd4b4d71
Local pid:
pubs:1071853
Source identifiers:
1071853
Deposit date:
2019-11-14

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