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Medial orbitofrontal cortex modulates associative learning between environmental cues and reward probability

Abstract:

It has recently been recognised that orbitofrontal cortex has two subdivisions that are anatomically and functionally distinct. Most rodent research has focused on the lateral subdivision, leaving the medial subdivision (mOFC) relatively unexplored. We recently showed that inhibiting mOFC neurons eliminated the differential impact of reward probability cues on discrimination accuracy in a sustained attention task. In the present study, we tested whether increasing mOFC neuronal activity in ra...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1037/bne0000178

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Experimental Psychology
Oxford college:
Magdalen College
Role:
Author
University of Otago More from this funder
Publisher:
American Psychological Association Publisher's website
Journal:
Behavioral Neuroscience Journal website
Volume:
131
Issue:
1
Pages:
1-10
Publication date:
2016-12-22
Acceptance date:
2016-11-08
DOI:
EISSN:
1939-0084
ISSN:
0735-7044
Pubs id:
pubs:692017
URN:
uri:e8718255-a26a-4577-a51b-b9b1b2dc6d45
UUID:
uuid:e8718255-a26a-4577-a51b-b9b1b2dc6d45
Local pid:
pubs:692017

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