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Basic statistical analysis in genetic case-control studies.

Abstract:

This protocol describes how to perform basic statistical analysis in a population-based genetic association case-control study. The steps described involve the (i) appropriate selection of measures of association and relevance of disease models; (ii) appropriate selection of tests of association; (iii) visualization and interpretation of results; (iv) consideration of appropriate methods to control for multiple testing; and (v) replication strategies. Assuming no previous experience with soft...

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Publication status:
Published

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Publisher copy:
10.1038/nprot.2010.182

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Role:
Author
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Journal:
Nature protocols
Volume:
6
Issue:
2
Pages:
121-133
Publication date:
2011-02-05
DOI:
EISSN:
1750-2799
ISSN:
1754-2189
URN:
uuid:e7e3a6b1-7baa-4280-955c-7d128f207aad
Source identifiers:
118024
Local pid:
pubs:118024

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