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Basic statistical analysis in genetic case-control studies.

Abstract:

This protocol describes how to perform basic statistical analysis in a population-based genetic association case-control study. The steps described involve the (i) appropriate selection of measures of association and relevance of disease models; (ii) appropriate selection of tests of association; (iii) visualization and interpretation of results; (iv) consideration of appropriate methods to control for multiple testing; and (v) replication strategies. Assuming no previous experience with soft...

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Publication status:
Published

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Publisher copy:
10.1038/nprot.2010.182

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author
Journal:
Nature protocols More from this journal
Volume:
6
Issue:
2
Pages:
121-133
Publication date:
2011-02-01
DOI:
EISSN:
1750-2799
ISSN:
1754-2189
Language:
English
Keywords:
Pubs id:
pubs:118024
UUID:
uuid:e7e3a6b1-7baa-4280-955c-7d128f207aad
Local pid:
pubs:118024
Source identifiers:
118024
Deposit date:
2012-12-19

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