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Journal article

Brain injury in COVID-19 is associated with dysregulated innate and adaptive immune responses

Abstract:

COVID-19 is associated with neurological complications including stroke, delirium and encephalitis. Furthermore, a post-viral syndrome dominated by neuropsychiatric symptoms is common, and is seemingly unrelated to COVID-19 severity. The true frequency and underlying mechanisms of neurological injury are unknown, but exaggerated host inflammatory responses appear to be a key driver of COVID-19 severity.

We investigated the dynamics of, and relationship between, serum markers of brai...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/brain/awac321

Authors


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Role:
Author
ORCID:
0000-0001-7042-7462
More by this author
Role:
Author
ORCID:
0000-0003-1877-2474

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Publisher:
Oxford University Press
Journal:
Brain More from this journal
Volume:
145
Issue:
11
Article number:
4097-4107
Publication date:
2022-09-06
Acceptance date:
2022-08-01
DOI:
EISSN:
1460-2156
ISSN:
0006-8950
Pmid:
36065116
Language:
English
Keywords:
Pubs id:
1277984
Local pid:
pubs:1277984
Deposit date:
2022-11-18

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