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Vinyl Weinreb amides: A versatile alternative to vinyl ketone substrates for the Heck arylation

Abstract:
This paper describes the use of unsaturated Weinreb amides as excellent substrates for the Heck reaction. Subsequent derivatization of the products with organometallic reagents allowed access to a variety of substituted vinyl ketones that could not have been prepared directly via Heck reaction on unsaturated ketone precursors. © 2013 Elsevier Ltd. All rights reserved.

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Publisher copy:
10.1016/j.tet.2013.03.009

Authors


Journal:
Tetrahedron
Volume:
69
Issue:
18
Pages:
3690-3697
Publication date:
2013-05-06
DOI:
EISSN:
1464-5416
ISSN:
0040-4020
URN:
uuid:e7876250-d1ca-437c-8173-0e8b102a301e
Source identifiers:
395211
Local pid:
pubs:395211

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