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Architecture of the Trypanosoma brucei nucleus during interphase and mitosis.

Abstract:

The structural basis of mitosis, spindle organisation and chromosome segregation, in the unicellular parasite Trypanosoma brucei is poorly understood. Here, using immunocytochemistry, fluorescent in situ hybridisation and electron microscopy, we provide a detailed analysis of mitosis in this parasite. We describe the organisation of the mitotic spindle during different stages of mitosis, the complex ultrastructure of kinetochores and the identification of a potential spindle-organising centre...

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Publication status:
Published

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Publisher copy:
10.1007/s004120050402

Authors


Ogbadoyi, E More by this author
Ersfeld, K More by this author
Robinson, D More by this author
Sherwin, T More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Journal:
Chromosoma
Volume:
108
Issue:
8
Pages:
501-513
Publication date:
2000-03-05
DOI:
EISSN:
1432-0886
ISSN:
0009-5915
URN:
uuid:e7800f64-6521-4bf3-bc0e-7564fd1eb297
Source identifiers:
26471
Local pid:
pubs:26471

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