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Validation of a Metastatic Assay using biopsies to improve risk stratification in patients with prostate cancer treated with radical radiation therapy.

Abstract:

Background

Radiotherapy is an effective treatment of intermediate/high-risk locally advanced prostate cancer, however,>30% of patients relapse within 5 years. Clinicopathological parameters currently fail to identify patients prone to systemic relapse and those whom treatment intensification may be beneficial. The purpose of this study was to independently validate the performance of a 70-gene Metastatic Assay in a cohort of diagnostic biopsies from patients treated with radic...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/annonc/mdx637

Authors


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Name:
Northern Ireland Experimental Cancer Medicine Centre
More from this funder
Name:
Public Health Agency of Northern Ireland
More from this funder
Name:
Movember Prostate Cancer UK Centre of Excellence
Publisher:
Oxford University Press
Journal:
Annals of Oncology More from this journal
Publication date:
2017-10-01
DOI:
EISSN:
1569-8041
ISSN:
0923-7534
Pmid:
29045551
Language:
English
Keywords:
Pubs id:
pubs:817465
UUID:
uuid:e774eeba-d558-4bda-b3ae-8261f50cb217
Local pid:
pubs:817465
Source identifiers:
817465
Deposit date:
2018-01-11

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