Journal article icon

Journal article

Increased cationic amino acid flux through a newly expressed transporter in cells overproducing nitric oxide from patients with septic shock.

Abstract:

Increased production of nitric oxide (NO) is thought to be a factor in the pathogenesis of many human diseases - among them the hypotension that often accompanies sepsis. The supply of the cationic amino acid arginine is known to be rate-limiting for NO production. We hypothesized that cationic amino acid transport might be increased in cells producing excess NO from patients with septic shock. Peripheral blood mononuclear cells were isolated from patients with sepsis and from healthy control...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1042/cs20010329

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Journal:
Clinical science (London, England : 1979) More from this journal
Volume:
102
Issue:
6
Pages:
645-650
Publication date:
2002-06-01
DOI:
EISSN:
1470-8736
ISSN:
0143-5221

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP