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Adipose tissue and the insulin resistance syndrome.

Abstract:

Obesity is associated with insulin resistance. Insulin resistance underlies a constellation of adverse metabolic and physiological changes (the insulin resistance syndrome) which is a strong risk factor for development of type 2 diabetes and CHD. The present article discusses how accumulation of triacylglycerol in adipocytes can lead to deterioration of the responsiveness of glucose metabolism in other tissues. Lipodystrophy, lack of adipose tissue, is also associated with insulin resistance....

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Publication status:
Published

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Publisher copy:
10.1079/PNS200195

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM
Journal:
The Proceedings of the Nutrition Society
Volume:
60
Issue:
3
Pages:
375-380
Publication date:
2001-08-05
DOI:
EISSN:
1475-2719
ISSN:
0029-6651
URN:
uuid:e751ce82-5f78-4852-8d07-e640280a0b6b
Source identifiers:
16099
Local pid:
pubs:16099

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