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Establishment of a therapeutic ratio for gamma knife radiosurgery of trigeminal neuralgia: the critical importance of biologically effective dose versus physical dose

Abstract:

Objective

How variations of treatment time affect the safety and efficacy of Gamma Knife (GK) radiosurgery is a matter of considerable debate. With the relative simplicity of treatment planning for trigeminal neuralgia (TN), this question has been addressed in a group of these patients. Using the concept of the biologically effective dose (BED), the effect of the two key variables, dose and treatment time, were considered.

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.wneu.2019.10.021

Authors


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Role:
Author
ORCID:
0000-0001-6776-1486
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Institution:
University of Oxford
Oxford college:
Green Templeton College
Role:
Author
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Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Sub department:
CRUK/MRC Ox Inst for Radiation Oncology
Role:
Author
Publisher:
Elsevier
Journal:
World Neurosurgery More from this journal
Volume:
134
Pages:
e204-e213
Publication date:
2019-10-10
Acceptance date:
2019-10-03
DOI:
EISSN:
1878-8769
ISSN:
1878-8750
Pmid:
31606504
Language:
English
Keywords:
Pubs id:
1064151
Local pid:
pubs:1064151
Deposit date:
2020-06-03

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