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Journal article

Predicting the influence of microvascular structure on tumour response to radiotherapy

Abstract:

Objective: The purpose of this study is to investigate how theoretical predictions of tumour response to radiotherapy depend on the morphology and spatial representation of the microvascular network. Methods: A hybrid multiscale model, that couples a cellular automaton model of tumour growth with a model for oxygen transport from blood vessels, is used to predict the viable fraction of cells following one week of simulated radiotherapy. Both artificial and biologically derived three-dimension...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1109/TBME.2016.2606563

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Mathematical Institute
Role:
Author
Publisher:
Institute of Electrical and Electronics Engineers
Journal:
IEEE Transactions on Biomedical Engineering More from this journal
Volume:
64
Issue:
3
Pages:
504 - 511
Publication date:
2016-09-08
Acceptance date:
2016-07-31
DOI:
ISSN:
0018-9294
Pubs id:
pubs:641411
UUID:
uuid:e70500d9-d491-4f53-90a4-8960e60c0866
Local pid:
pubs:641411
Source identifiers:
641411
Deposit date:
2016-09-04

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