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Cryocooling and radiation damage in macromolecular crystallography.

Abstract:

Advances in cryocrystallographic techniques for macromolecular crystallography have been intimately intertwined with efforts to reduce the deleterious effects of X-ray damage inflicted during the collection of diffraction data. A brief overview of cryomethods and their rationale is given. This is followed by a summary of our current limited understanding of radiation damage in cryocooled crystals, investigations aimed at minimizing its effects and finally some developments which actually util...

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Publication status:
Published

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Publisher copy:
10.1107/s0907444905034207

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
Journal:
Acta crystallographica. Section D, Biological crystallography More from this journal
Volume:
62
Issue:
Pt 1
Pages:
32-47
Publication date:
2006-01-01
DOI:
EISSN:
1399-0047
ISSN:
0907-4449
Language:
English
Keywords:
Pubs id:
pubs:100116
UUID:
uuid:e704039c-1773-4fe0-826b-3675da7cb188
Local pid:
pubs:100116
Source identifiers:
100116
Deposit date:
2012-12-19

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