Journal article
The chromosome 6p22 haplotype associated with dyslexia reduces the expression of KIAA0319, a novel gene involved in neuronal migration.
- Abstract:
-
Dyslexia is one of the most prevalent childhood cognitive disorders, affecting approximately 5% of school-age children. We have recently identified a risk haplotype associated with dyslexia on chromosome 6p22.2 which spans the TTRAP gene and portions of THEM2 and KIAA0319. Here we show that in the presence of the risk haplotype, the expression of the KIAA0319 gene is reduced but the expression of the other two genes remains unaffected. Using in situ hybridization, we detect a very distinct ex...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Human molecular genetics
- Volume:
- 15
- Issue:
- 10
- Pages:
- 1659-1666
- Publication date:
- 2006-05-01
- DOI:
- EISSN:
-
1460-2083
- ISSN:
-
0964-6906
- Source identifiers:
-
24438
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:24438
- UUID:
-
uuid:e702e9ba-97c7-449e-9792-392f30b49a3d
- Local pid:
- pubs:24438
- Deposit date:
- 2012-12-19
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- Copyright date:
- 2006
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