Journal article icon

Journal article

Genome-wide transcriptome analysis reveals equine embryonic stem cell-derived tenocytes resemble fetal, not adult tenocytes

Abstract:

Background:
Tendon injuries occur frequently in human and equine athletes. Treatment options are limited, and the prognosis is often poor with functionally deficient scar tissue resulting. Fetal tendon injuries in contrast are capable of healing without forming scar tissue. Embryonic stem cells (ESCs) may provide a potential cellular therapeutic to improve adult tendon regeneration; however, whether they can mimic the properties of fetal tenocytes is unknown. To this...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1186/s13287-020-01692-w

Authors


More by this author
Role:
Author
ORCID:
0000-0003-3823-9618
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Botnar Research Centre
Role:
Author
Publisher:
BioMed Central
Journal:
Stem Cell Research and Therapy More from this journal
Volume:
11
Article number:
184
Publication date:
2020-05-19
Acceptance date:
2020-04-28
DOI:
EISSN:
1757-6512
Language:
English
Keywords:
Pubs id:
1107431
Local pid:
pubs:1107431
Deposit date:
2020-05-29

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP