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Metabolism of very-low-density lipoprotein and chylomicrons by streptozotocin-induced diabetic rat heart: effects of diabetes and lipoprotein preference.

Abstract:

Very-low-density lipoprotein (VLDL) and chylomicrons (CM) are major sources of fatty acid supply to the heart, but little is known about their metabolism in diabetic myocardium. To investigate this, working hearts isolated from control rats and diabetic rats 2 wk following streptozotocin (STZ) injection were perfused with control and diabetic lipoproteins. Analysis of the diabetic lipoproteins showed that both VLDL and CM were altered compared with control lipoproteins; both were smaller and ...

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Publisher copy:
10.1152/ajpendo.90260.2008

Authors


Journal:
American journal of physiology. Endocrinology and metabolism
Volume:
295
Issue:
5
Pages:
E1106-E1116
Publication date:
2008-11-05
DOI:
EISSN:
1522-1555
ISSN:
0193-1849
URN:
uuid:e6bdd12d-294a-448b-9398-657c2cbf4bee
Source identifiers:
239039
Local pid:
pubs:239039

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