Improving the diagnosis and treatment of urinary tract infection in young children in primary care: Results from the DUTY prospective diagnostic cohort study.

Journal article

Purpose

Up to 50% of urinary tract infections (UTIs) in young children are missed in primary care. Urine culture is essential for diagnosis, but urine collection is often difficult. Our aim was to derive and internally validate a 2-step clinical rule using (1) symptoms and signs to select children for urine collection; and (2) symptoms, signs, and dipstick testing to guide antibiotic treatment.

Methods

We recruited acutely unwell children aged under 5 years from 2...

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Authors: Hay, A; Sterne, J; Hood, K; Little, P; Delaney, B

• Publication status: Published
• Peer review status: Peer reviewed
• Publisher: Annals of Family Medicine, Inc
• Journal: Annals of Family Medicine
• Volume: 14
• Issue: 4
• Pages: 325-336
• Publication date: 2016-07-01
• Acceptance date: 2016-04-07
• DOI: 10.1370/afm.1954
• EISSN: 1544-1717
• ISSN: 1544-1709
• Pmid: 27401420
• Language: English
• Keywords: Female; Humans; Primary Health Care; Urine Specimen Collection; Prospective Studies; Infant; Anti-Bacterial Agents; United Kingdom; Reference Standards; Sensitivity and Specificity; Urinary Tract Infections; Male; Severity of Illness Index; Child, Preschool; Urinalysis