- Abstract:
-
The mutation rate of the mitochondrial control region has been widely used to calibrate human population history. However, estimates of the mutation rate in this region have spanned two orders of magnitude. To readdress this rate, we sequenced the mtDNA control region in 272 individuals, who were related by a total of 705 mtDNA transmission events, from 26 large Icelandic pedigrees. Three base substitutions were observed, and the mutation rate across the two hypervariable regions was estimate...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1086/302902
-
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- Journal:
- American journal of human genetics
- Volume:
- 66
- Issue:
- 5
- Pages:
- 1599-1609
- Publication date:
- 2000-05-05
- DOI:
- EISSN:
-
1537-6605
- ISSN:
-
0002-9297
- URN:
-
uuid:e6a1ae9a-3125-43e4-9a0b-fe18af42b367
- Source identifiers:
-
50040
- Local pid:
- pubs:50040
- Copyright date:
- 2000
Journal article
The mutation rate in the human mtDNA control region.
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