Journal article
Regulation of growth differentiation factor 15 expression by intracellular iron.
- Abstract:
-
Growth differentiation factor 15 (GDF15) is a divergent member of the transforming growth factor-beta superfamily and has been identified in different contexts as a hypoxia-inducible gene product and as a molecule involved in hepcidin regulation. The biology of iron and oxygen is closely related, and known regulatory pathways involving hypoxia-inducible factor (HIF) and iron-regulatory proteins (IRPs) are responsive to both these stimuli. We therefore sought to characterize the regulation of ...
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- Publication status:
- Published
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- Publisher copy:
- 10.1182/blood-2008-07-170431
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Authors
Bibliographic Details
- Journal:
- Blood
- Volume:
- 113
- Issue:
- 7
- Pages:
- 1555-1563
- Publication date:
- 2009-02-01
- DOI:
- EISSN:
-
1528-0020
- ISSN:
-
0006-4971
- Source identifiers:
-
10719
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:10719
- UUID:
-
uuid:e69782fa-ea61-4056-b9ab-ad450a38861b
- Local pid:
- pubs:10719
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2009
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