Journal article
Analysis of recurrent events with an associated informative dropout time: Application of the joint frailty model
- Abstract:
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This paper considers the analysis of a repeat event outcome in clinical trials of chronic diseases in the context of dependent censoring (e.g. mortality). It has particular application in the context of recurrent heart failure hospitalisations in trials of heart failure. Semi‐parametric joint frailty models (JFMs) simultaneously analyse recurrent heart failure hospitalisations and time to cardiovascular death, estimating distinct hazard ratios whilst individual‐specific latent variables induc...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Version of record, pdf, 314.1KB, Terms of use)
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- Publisher copy:
- 10.1002/sim.6853
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Funding
Bibliographic Details
- Publisher:
- Wiley
- Journal:
- Statistics in Medicine More from this journal
- Volume:
- 35
- Issue:
- 13
- Pages:
- 2195-2205
- Publication date:
- 2016-01-10
- Acceptance date:
- 2015-11-26
- DOI:
- EISSN:
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1097-0258
- ISSN:
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0277-6715
- Pmid:
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26751714
Item Description
- Language:
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English
- Keywords:
- Pubs id:
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pubs:587580
- UUID:
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uuid:e6873d7c-bbde-49bc-aaeb-9e93a88ef54f
- Local pid:
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pubs:587580
- Source identifiers:
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587580
- Deposit date:
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2019-01-22
Terms of use
- Copyright holder:
- Rogers et al
- Copyright date:
- 2016
- Notes:
- © 2016 The Authors. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
- Licence:
- CC Attribution (CC BY)
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