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Journal article

The genetics of complex cholestatic disorders.

Abstract:

Cholestatic liver diseases are caused by a range of hepatobiliary insults and involve complex interactions among environmental and genetic factors. Little is known about the pathogenic mechanisms of specific cholestatic diseases, which has limited our ability to manage patients with these disorders. However, recent genome-wide studies have provided insight into the pathogenesis of gallstones, primary biliary cirrhosis, and primary sclerosing cholangitis. A lithogenic variant in the gene that ...

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Publication status:
Published

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Journal:
Gastroenterology
Volume:
144
Issue:
7
Pages:
1357-1374
Publication date:
2013-06-05
DOI:
EISSN:
1528-0012
ISSN:
0016-5085
URN:
uuid:e67d1bce-a9c0-48b2-8b55-87b8cafa9715
Source identifiers:
414698
Local pid:
pubs:414698

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