BACKGROUND: Hypoxia may contribute to the pathogenesis of various diseases of the vascular wall. Hypoxia-inducible factors (HIFs) are nuclear transcriptional factors that regulate the transcription of genes that mediate cellular and tissue homeostatic responses to altered oxygenation. This article reviews the published literature on and discusses the role of the HIF pathway in diseases involving the vascular wall, including atherosclerosis, arterial aneurysms, pulmonary hypertension, vascula...Expand abstract
- Publication status:
- Publisher copy:
- Copyright date:
Hypoxia-inducible factor pathway and diseases of the vascular wall.
If you are the owner of this record, you can report an update to it here: Report update to this record