The extent to which natural selection shapes diversity within populations is a key ques- tion for population genetics. Thus, there is considerable interest in quantifying the strength of selection. In this thesis a full likelihood approach for inference about selec- tion at a single site within an otherwise neutral fully-linked sequence of sites is devel- oped. Integral to many of the ideas introduced in this thesis is the reversibility of the diffusion process, and some past approaches to...Expand abstract
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- Graham Coop
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The likelihood of gene trees under selective models.
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