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Malaria in a nonimmune population after extended chloroquine or primaquine prophylaxis.

Abstract:

Extended chemoprophylaxis against endemic malaria raises concern with regard to susceptibility after ceasing use of the drug. In this study, we measured attack rates of malaria among adult men for 28 weeks after they ended one year of prophylaxis using either weekly chloroquine (5 mg base/kg, n = 20), daily primaquine (0.5 mg base/kg, n = 30), or a placebo of primaquine (n = 41). The 28-week incidence densities, times to parasitemia, parasite densities, and symptoms of primary post-prophylaxi...

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Publication status:
Published

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Authors


Fryauff, DJ More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Awalludin, M More by this author
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Journal:
The American journal of tropical medicine and hygiene
Volume:
56
Issue:
2
Pages:
137-140
Publication date:
1997-02-05
EISSN:
1476-1645
ISSN:
0002-9637
URN:
uuid:e5e4cdde-45a1-414e-b058-1ca0372884bb
Source identifiers:
81739
Local pid:
pubs:81739

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