- Abstract:
-
Hepatitis C virus (HCV) sets up persistent infection in the majority of those exposed. It is likely that, as with other persistent viral infections, the efficacy of T-lymphocyte responses influences long-term outcome. However, little is known about the functional capacity of HCV-specific T-lymphocyte responses induced after acute infection. We investigated this by using major histocompatibility complex class I-peptide tetrameric complexes (tetramers), which allow direct detection of specific ...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1128/jvi.75.12.5550-5558.2001
-
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- Journal:
- Journal of virology
- Volume:
- 75
- Issue:
- 12
- Pages:
- 5550-5558
- Publication date:
- 2001-06-05
- DOI:
- EISSN:
-
1098-5514
- ISSN:
-
0022-538X
- URN:
-
uuid:e5dfa12a-86ef-4f5b-bee1-957d8f49d2e2
- Source identifiers:
-
11326
- Local pid:
- pubs:11326
- Copyright date:
- 2001
Journal article
Sustained dysfunction of antiviral CD8+ T lymphocytes after infection with hepatitis C virus.
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