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Untangling the relationship between diet and visceral fat mass through blood metabolomics and gut microbiome profiling

Abstract:

Higher visceral fat mass (VFM) is associated with an increased risk for developing cardio-metabolic diseases. The mechanisms by which an unhealthy diet pattern may influence visceral fat (VF) development has yet to be examined through cutting-edge multi-omic methods. Therefore, our objective was to examine the dietary influences on VFM and identify gut microbiome and metabolite profiles that link food intakes to VFM.In 2218 twins with VFM, food intake and metabolomics data available we identi...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1038/ijo.2017.70

Authors


Pallister, T More by this author
Jackson, MA More by this author
Martin, TC More by this author
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Department:
Oxford, MSD, NDM, Human Genetics Wt Centre, BDI-NDM
Jennings, A More by this author
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Grant:
FP7 project HEALS (Health and Environment-wide Associations based on Large population Surveys) Project No 603946
Wellcome Trust More from this funder
National Institute for Health Research More from this funder
Publisher:
Springer Nature Publisher's website
Journal:
International Journal of Obesity Journal website
Volume:
41
Issue:
7
Pages:
1106-1113
Publication date:
2017-04-04
Acceptance date:
2017-02-26
DOI:
EISSN:
1476-5497
ISSN:
0307-0565
Pubs id:
pubs:691941
URN:
uri:e5ce1e4d-6742-4b57-b47f-e3b0d1356f89
UUID:
uuid:e5ce1e4d-6742-4b57-b47f-e3b0d1356f89
Local pid:
pubs:691941
Language:
English

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