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CalQuo 2 : Automated Fourier-space, population-level quantification of global intracellular calcium responses

Abstract:

Intracellular calcium acts as a secondary messenger in a wide variety of crucial biological signaling processes. Advances in fluorescence microscopy and calcium sensitive dyes has led to the routine quantification of calcium responses in non-excitable cells. However, the automatization of global intracellular calcium analysis at the single-cell level within a large population simultaneously remains challenging. One software, CalQuo (Calcium Quantification), offers some automatic features in c...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/s41598-017-05322-z

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
Weatherall Insti. of Molecular Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
Weatherall Insti. of Molecular Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Oxford college:
Balliol College
Role:
Author
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Grant:
Institutional Strategic Support Fund
More from this funder
Grant:
MC_UU_12010/unitprogrammesG0902418
MC_UU_12025
John Fell Fund More from this funder
Publisher:
Springer Nature Publisher's website
Journal:
Scientific Reports Journal website
Volume:
7
Issue:
1
Article number:
5416
Publication date:
2017-07-14
Acceptance date:
2017-06-09
DOI:
ISSN:
2045-2322
Source identifiers:
708688
Pubs id:
pubs:708688
UUID:
uuid:e5b5dda1-2bc8-42b6-8f98-6c1acbb197df
Local pid:
pubs:708688
Deposit date:
2017-07-20

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