- Abstract:
-
Background: Clinical trials in cystic fibrosis (CF) have been hindered by the paucity of well characterised and clinically relevant outcome measures. Aim: To evaluate a range of conventional and novel biomarkers of CF lung disease in a multicentre setting as a contributing study in selecting outcome assays for a clinical trial of CFTR gene therapy. Methods: A multicentre observational study of adult and paediatric patients with CF (>10 years) treated for a physician-defined exacerbation of...
Expand abstract - Publisher copy:
- 10.1136/thoraxjnl-2012-202538
-
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- Journal:
- Thorax
- Volume:
- 68
- Issue:
- 6
- Pages:
- 532-539
- Publication date:
- 2013-06-05
- DOI:
- EISSN:
-
1468-3296
- ISSN:
-
0040-6376
- URN:
-
uuid:e59dab40-0388-4f09-9440-1c2241d1ce7d
- Source identifiers:
-
403562
- Local pid:
- pubs:403562
- Language:
- English
- Copyright date:
- 2013
Journal article
Changes in physiological, functional and structural markers of cystic fibrosis lung disease with treatment of a pulmonary exacerbation
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